U4757
Sigma
Anti-Urocortin antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
| MDL number: | MFCD01632996 |
Description
| Immunogen | synthetic peptide corresponding to the C-terminal of human urocortin (amino acids 25-40 with N-terminally added lysine) conjugated to KLH. The immunogen sequence (human) corresponds to pro-urocortin (amino acids 105-120) and is identical in rat urocortin. |
| Specificity | The antibody is evaluated for activity and specificity by radioimmunoassay (RIA) and immunohistochemistry. The antibody does not cross-react with human or rat CRF (6-33), sheep CRF, PACAP38, human ACTH, human ACTH (18-39), and sauvagine. |
| Physical form | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide |
Properties
| antibody form | IgG fraction of antiserum |
| clone | (polyclonal) |
| form | buffered aqueous solution |
| species reactivity | human, rat |
| application(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200 using microwave-treated sections of human placental tissue |
| quantitative precipitin assay: 1:10,000 using 125I-Tyr0-Urocortin (rat) | |
| Gene Information | human ... UCN(7349) |
| rat ... Ucn(29151) | |
| shipped in | dry ice |
| storage temp. | −20°C |
Safety
| WGK Germany | 3 |
References
| reference | Ahanya, S., et al., Corticotropin-releasing factor inhibition of sheep fetal colonic contractility: mechanisms to prevent meconium passage in utero. Am. J. Obstet. Gynecol. 196, 357, (2007) Abstract |
